产品介绍
BioXcell InVivoPlus anti-mouse Ly6G 1A8单克隆抗体与小鼠Ly6G反应。Ly6G分子量为21-25kDa,是GPI锚定的细胞表面蛋白Ly-6超家族的成员,在细胞信号传导和细胞粘附中发挥作用。Ly6G在发育过程中由骨髓谱系中的细胞(包括单核细胞、巨噬细胞、粒细胞和嗜中性粒细胞)差异表达。单核细胞通常在发育过程中瞬时表达Ly6G,而成熟的粒细胞和外周嗜中性粒细胞保持表达,使Ly6G成为这些群体的良好细胞表面标志物。与BioXcell RB6-8C5抗体不同,1A8抗体与小鼠Ly6G特异性反应,而与Ly6C没有交叉反应性的报道。
 
 
产品详情
| 产品名称 | InVivoPlus anti-mouse Ly6G | 
| 产品货号 | BP0075-1 | 
| 产品规格 | 5/25/50/100mg | 
| 反应种属 | Mouse | 
| 克隆号 | 1A8 | 
| 同种型 | Rat IgG2a, κ | 
| 免疫原 | EL4J cells transfected with Ly6G | 
| 实验应用 | in vivo neutrophil depletion in vivo MDSC depletion Immunofluorescence Immunohistochemistry (paraffin) Immunohistochemistry (frozen) Flow cytometry | 
| 产品形式 | PBS, pH 7.0,Contains no stabilizers or preservatives | 
| 纯度 | >95%, Determined by SDS-PAGE | 
| 聚合 | <5%, Determined by SEC | 
| 无菌处理 | 0.2 µm filtration | 
| 纯化方式 | Protein G | 
| RRID | AB_1107721 | 
| 分子量 | 150 kDa | 
| 小鼠病原检测 | Ectromelia/Mousepox Virus: Negative Hantavirus: Negative K Virus: Negative Lactate Dehydrogenase-Elevating Virus: Negative Lymphocytic Choriomeningitis virus: Negative Mouse Adenovirus: Negative Mouse Cytomegalovirus: Negative Mouse Hepatitis Virus: Negative Mouse Minute Virus: Negative Mouse Norovirus: Negative Mouse Parvovirus: Negative Mouse Rotavirus: Negative Mycoplasma Pulmonis: Negative Pneumonia Virus of Mice: Negative Polyoma Virus: Negative Reovirus Screen: Negative Sendai Virus: Negative Theiler’s Murine Encephalomyelitis: Negative | 
| 保存条件 | 抗体原液保存在4°C,不能冷冻保存。 | 
| 推荐同型对照 | InVivoPlus rat IgG2a isotype control, anti-trinitrophenol(货号BP0089) | 
| 推荐抗体稀释液 | InVivoPure pH 7.0 Dilution Buffer(货号IP0070) | 
为什么选择InVivoPlus抗体?
InVivoPlus级别的产品内毒素含量更低,经过多种实验验证,更适合用于体内实验研究
 
该产品自上市已被多篇SCI文献引用,品质有保证,以下是部分已发表的文献引用:
| 应用 | 文章 | 
| 体内中性粒细胞耗竭 (in vivo neutrophil depletion) | 1. Davis, R. W. t., et al. (2018). 'Luminol Chemiluminescence Reports Photodynamic Therapy-Generated Neutrophil Activity In Vivo and Serves as a Biomarker of Therapeutic Efficacy' Photochem Photobiol . 2. Moynihan, K. D., et al. (2016). 'Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses' Nat Med. doi : 10.1038/nm.4200. 3. Conde, P., et al. (2015). 'DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance' Immunity 42(6): 1143-1158. 4. Griseri, T., et al. (2015). 'Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis' Immunity 43(1): 187-199. 5. Yamada, D. H., et al. (2015). 'Suppression of Fcgamma-receptor-mediated antibody effector function during persistent viral infection' Immunity 42(2): 379-390. 6. Ellis, G. T., et al. (2015). 'TRAIL+ monocytes and monocyte-related cells cause lung damage and thereby increase susceptibility to influenza-Streptococcus pneumoniae coinfection' EMBO Rep 16(9): 1203-1218. 7. Deshmukh, H. S., et al. (2014). 'The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice' Nat Med 20(5): 524-530. | 
| 体内中性粒细胞耗竭、流式细胞术、免疫组化石蜡切片(in vivo neutrophil depletion, Flow Cytometry, Immunohistochemistry (paraffin)) | Coffelt, S. B., et al. (2015). 'IL-17-producing gammadelta T cells and neutrophils conspire to promote breast cancer metastasis' Nature 522(7556): 345-348. | 
| 体内中性粒细胞耗竭、流式细胞术、免疫组化石蜡切片、免疫组化冰冻切片(in vivo neutrophil depletion, Flow Cytometry, Immunohistochemistry (paraffin), Immunohistochemistry (frozen)) | 欣博盛生物科技有限公司 商家主页地 址: 深圳福田区梅华路105号多丽工业区科技楼605 联系人: Miss Yao 电 话: 0755-26755892(深圳) 010-88594029(北京) 021-34613729(上海) 020-87615159 (广州) 传 真: 0755-26755877 Email:market@neobioscience.com 相关咨询双十一狂欢季,欣博盛ELISA试剂盒买二送一! (暂无发布时间 浏览数:2853) 凝集素应用手册 (Western Blotting- 多色荧光法) (暂无发布时间 浏览数:5869) 凝集素应用手册 ( 酶分析—糖基转移酶/糖苷酶 ) (暂无发布时间 浏览数:3832) 文献选读:慢性肾病中的嵌合性Progerin表达与早发性血管老化 (暂无发布时间 浏览数:8693) 从信号到代谢:GeneTex高质量GPCR抗体推动肥胖研究新进展 (暂无发布时间 浏览数:12967) StressMarq邀您相约第九届中国神经科学学会神经退行性疾病分会年会 (暂无发布时间 浏览数:12471) 文献选读:靶向胶质母细胞瘤神经元–肿瘤网络 (暂无发布时间 浏览数:15381) GeneTex HIF1α 抗体:推动缺氧研究 (暂无发布时间 浏览数:12982) StressMarq&欣博盛生物:神经退行性疾病相关单体、寡聚体、预制原纤维 (暂无发布时间 浏览数:14045) 【前沿解读】中性粒细胞弹性蛋白酶在癌症治疗中的潜力探索 (暂无发布时间 浏览数:18368) ADVERTISEMENT | 
